NanoFense

NanoFense is a proprietary antimicrobial coating technology developed by NanoSafe Inc. that utilizes silver nanoparticles to provide persistent protection against a broad spectrum of pathogens, including bacteria, viruses, and fungi. The technology is primarily designed for integration into textiles and surfaces, such as face masks and personal protective equipment (PPE), to enhance their self-disinfecting capabilities. The mechanism of action involves the controlled, sustained release of silver ions ($Ag^+$), which exert antimicrobial effects by disrupting microbial cell membranes, denaturing essential metabolic enzymes through binding with thiol groups, and interfering with genomic replication by interacting with microbial DNA. NanoFense was notably deployed during the COVID-19 pandemic to reduce the risk of pathogen transmission via medical fabrics and surfaces. As a material-integrated solution, it is typically categorized as a medical device component or a biocidal treatment rather than a systemic pharmaceutical agent.

Brand names

NanoFense

Other names

NanoFense antimicrobial coating