Drug intelligence / Profile preview

naoluoshuning

Development stage
Unknown
Lead developer
China Academy of Chinese Medical Sciences
Modality
Small Molecules
Administration
Oral
01

Overview

Naoluoshuning is a Traditional Chinese Medicine (TCM) compound preparation developed by the Institute of Clinical Basic Medicine at the China Academy of Chinese Medical Sciences. It is specifically indicated for the treatment of vascular dementia (VD), a condition characterized by cognitive decline resulting from ischemic or hemorrhagic brain lesions. The formula is designed to address the TCM syndrome of phlegm-stasis blocking the orifices, which is believed to be a primary driver of cognitive impairment in VD patients. Mechanistically, Naoluoshuning is thought to exert its therapeutic effects by improving cerebral microcirculation, reducing neuroinflammation, and inhibiting neuronal apoptosis. Clinical evaluations have demonstrated its potential to improve cognitive scores, such as the Mini-Mental State Examination (MMSE), and enhance the quality of life for patients with mild to moderate vascular dementia.

Brand names
Naoluoshuning
Other names
脑络疏宁Naoluo Shuning
02

Targets

Acetylcholinesterase

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