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naoshuantong
- Development stage
- Phase 4
- Lead developer
- Buchang Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Naoshuantong is a Traditional Chinese Medicine (TCM) formulation primarily used in China for the treatment of ischemic stroke and other cerebrovascular diseases. It is a multi-component mixture typically containing extracts from *Hirudo* (leech), *Radix Astragali*, *Radix Salviae Miltiorrhizae*, *Radix et Rhizoma Notoginseng*, and *Rhizoma Chuanxiong*. The therapeutic mechanism is attributed to its ability to inhibit thrombin activity (via hirudin from the leech component), suppress platelet aggregation, improve microcirculation, and provide neuroprotection against ischemic injury. It is widely marketed in China and is currently being evaluated in clinical trials to further establish its efficacy in reducing stroke recurrence in high-risk populations.
- Brand names
- Naoshuantong Capsule
- Other names
- Naoshuantong Jiaonang
02
Targets
ALB (Human serum albumin)CASP3 (Caspase-3)TP53 (Cellular Tumor Antigen p53 R175H)VEGFA (Vascular endothelial growth factor A)F2 (Thrombin)
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