naphazoline + chlorphenamine

Vasocedine is a combination pharmaceutical product primarily used as a nasal decongestant and antihistamine. It contains naphazoline, a sympathomimetic amine that acts as a potent vasoconstrictor by stimulating alpha-adrenergic receptors in the nasal mucosa, thereby reducing swelling and congestion. The second component, chlorphenamine, is a first-generation antihistamine that acts as a competitive antagonist at H1 histamine receptors, helping to alleviate allergic symptoms such as sneezing and rhinorrhea. The product is commonly marketed in Belgium by Qualiphar and has been the subject of formulation research at institutions like Ghent University (Universiteit Gent), particularly regarding nasal drug delivery systems.

Brand names

Vasocedine

Other names

naphazoline nitrate + chlorphenamine maleate