naphazoline + pheniramine

**Naphazoline + pheniramine** is an ophthalmic combination drug containing a sympathomimetic vasoconstrictor (naphazoline) and a first-generation antihistamine (pheniramine). It is used as eye drops for the temporary relief of itching and redness associated with allergic conjunctivitis. - **Naphazoline** acts by constricting the blood vessels in the eye, thereby reducing redness and swelling. It is classified as a sympathomimetic amine (vasoconstrictor/decongestant). - **Pheniramine** is an H1 histamine receptor antagonist that blocks the action of histamine released during allergic reactions, relieving itching and irritation[1][3][6]. The combination is available over-the-counter and was first approved for clinical use in the United States in 1994[3].

Brand names

Naphcon-AOpcon-AVisine-AAK-Con-AVisine Multi-Action Eye Allergy Relief

Other names

naphazoline/pheniraminenaphazoline hydrochloride + pheniramine maleate