Drug intelligence / Profile preview

naphazoline hydrochloride + glycerin + polysorbate 80

Development stage
Unknown
Lead developer
Prestige Consumer Healthcare
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

Clear Eyes Triple Relief is an over-the-counter (OTC) ophthalmic solution marketed by Prestige Consumer Healthcare under the Clear Eyes brand. It is a multi-action formulation designed to provide relief from three common ocular symptoms: redness, dryness, and irritation. The product contains naphazoline hydrochloride, a sympathomimetic amine that acts as a vasoconstrictor by stimulating alpha-adrenergic receptors in the conjunctival arterioles, thereby reducing ocular congestion and redness. Additionally, the formulation includes glycerin and polysorbate 80, which function as demulcents and lubricants. These ingredients provide a protective film over the ocular surface, helping to soothe irritation and alleviate discomfort associated with dry eyes and environmental factors.

Brand names
Clear Eyes Triple ReliefTriple Relief
02

Targets

ADRA1A (α1A)ADRA2A (α2A)

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