naphthalene disulfonate ethyl cholate ammonium

Naphthalene disulfonate ethyl cholate ammonium is a small molecule choleretic agent being developed by Yangtze River Pharmaceutical Group. It is intended for the treatment of various gastrointestinal and biliary disorders, including nausea, vomiting, loss of appetite, abdominal distension, chronic gastritis, and biliary dyskinesia. The drug is also used to manage postoperative digestive tract dysfunction. Its primary mechanism of action involves the stimulation of bile secretion and flow, which facilitates the digestion and absorption of dietary fats and helps alleviate symptoms associated with biliary stasis. Clinical development has included Phase 1 pharmacokinetic studies in healthy Chinese subjects to evaluate its safety and dosing profile.

Other names

ammonium ethyl cholate naphthalene disulfonatenaphthalene-1,5-disulfonate ethyl cholate ammonium