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Nasalate
- Development stage
- Unknown
- Lead developer
- Paedpharm
- Modality
- Small Molecules
- Administration
- Intranasal, Topical
01
Overview
Nasalate is an over-the-counter (OTC) topical nasal cream developed and marketed by Care Pharmaceuticals, primarily in Australia. It is a combination medication containing chlorhexidine hydrochloride, an antiseptic agent, and phenylephrine hydrochloride, a decongestant. The product is indicated for the treatment of nasal vestibulitis (infection and inflammation of the nasal vestibule), post-operative nasal care to prevent infection and crusting, and the relief of nasal congestion associated with colds and sinusitis. Chlorhexidine provides broad-spectrum antimicrobial activity by disrupting microbial cell membranes, while phenylephrine acts as a selective alpha-1 adrenergic receptor agonist to reduce swelling of the nasal mucosa and improve airflow.
- Brand names
- Nasalate
- Other names
- Nasalate Cream
02
Targets
ADRA1A (α1A)
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