Drug intelligence / Profile preview

NASHA-L

Development stage
Unknown
Lead developer
Galderma
Administration
Subcutaneous, Intradermal
01

Overview

NASHA-L is a **non-animal stabilized hyaluronic acid** injectable gel formulation containing cross-linked hyaluronic acid and lidocaine, used primarily as a soft-tissue filler in aesthetic medicine. In published comparative studies and regulatory materials, NASHA-L refers to the **firm NASHA technology hyaluronic acid gel corresponding to Restylane Lyft with lidocaine**, a 20 mg/mL hyaluronic acid product generated by *Streptococcus* fermentation, chemically cross-linked with BDDE and supplied as a sterile injectable gel. Its therapeutic effect is primarily **mechanical tissue augmentation and volume restoration** rather than receptor-mediated pharmacology, with lidocaine included to reduce injection-associated pain. The product lineage was originally developed by Q-Med and is now part of the Galderma Restylane portfolio, with approvals and commercial use in facial contouring, correction of facial folds and wrinkles, and hand augmentation depending on jurisdiction.

Other names
non-animal stabilized hyaluronic acid lidocainehyaluronic acid injectable gel with lidocaine

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