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National Inst. of Pharma Education and Research (NIPER) VEGFR-2 compound 9j
- Development stage
- Preclinical
- Lead developer
- National Institute of Pharmaceutical Education and Research
01
Overview
National Inst. of Pharma Education and Research (NIPER) VEGFR-2 compound 9j: sourced facts only. name: "Additionally, enzymatic assays highlight the dual inhibitory activity of 9j against tubulin polymerization (IC50 = 1.1 μM) and VEGFR-2 kinase (IC50 = 0.95 ± 0.5 μM)." [PMID:41183291]; target: "Additionally, enzymatic assays highlight the dual inhibitory activity of 9j against tubulin polymerization (IC50 = 1.1 μM) and VEGFR-2 kinase (IC50 = 0.95 ± 0.5 μM)." [PMID:41183291]; developer: "Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, 500037, India." [PMID:41183291]; stage: "Among the synthesized compounds, 9j demonstrates remarkable potency against A549 (lung cancer) cell line with an IC50 value of 0.89 ± 0.14 μM." [PMID:41183291]
02
Targets
VEGFR2 (Vascular endothelial growth factor receptor 2)
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