Drug intelligence / Profile preview

Natrosol 4% Gel

Development stage
Unknown
Lead developer
Ashland
Modality
Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

Natrosol 4% Gel is a hydroxyethylcellulose-based topical formulation used as a placebo control in clinical research conducted by the Universidade Federal do Para. It is specifically utilized in Phase 1 clinical trials to evaluate the efficacy of experimental treatments, such as cannabidiol (CBD) gels, for the management of dentin sensitivity (tooth sensitivity) triggered by professional tooth bleaching with 35% hydrogen peroxide. Hydroxyethylcellulose is a non-ionic, water-soluble polymer that acts as a thickening and gelling agent, providing a vehicle that mimics the consistency of active treatments without containing active desensitizing ingredients like potassium nitrate or CBD.

Brand names
Natrosol
Other names
hydroxyethylcelluloseHECNatrosol-based gel 4%

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