Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
natto
- Development stage
- Unknown
- Modality
- Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Recombinant Proteins and Enzymes
- Administration
- Oral
01
Overview
Natto is a traditional Japanese food made from boiled soybeans fermented with the bacterium Bacillus subtilis (also known as Bacillus subtilis var. natto). The fermentation process produces a sticky, stringy product with a strong flavor and odor. Natto is notable for its high content of the enzyme nattokinase, which has fibrinolytic (blood clot-dissolving) activity. Natto also contains significant amounts of vitamin K2 due to ongoing synthesis by B. subtilis in the gut after consumption. Traditionally consumed as a food in Japan for centuries, natto is associated with potential cardiovascular benefits such as improved blood circulation and reduced risk of thrombosis; however, robust clinical evidence supporting these health claims remains limited[1][2][3][4][5][6]. Natto itself should not be confused with isolated nattokinase supplements.
- Other names
- nattofermented soybeansnattō
02
Targets
Fibrin (Factor Ia)PAI-1 (Plasminogen activator inhibitor type 1)
Beyond the preview
Go deeper on natto.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on natto.