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Nattokinn
- Development stage
- Unknown
- Lead developer
- INNventa Pharm
- Modality
- Small Molecules, Recombinant Proteins and Enzymes
- Administration
- Oral
01
Overview
Nattokinn is an oral dietary supplement formulated to support cardiovascular and circulatory health. It contains a combination of nattokinase (NSK-SD®), a potent fibrinolytic serine protease isolated from fermented soybeans (nattō), and folic acid in the active form of calcium-L-methylfolate. Nattokinase directly hydrolyzes fibrin clots, degrades fibrinogen, and inactivates plasminogen activator inhibitor-1 (PAI-1), while also promoting endogenous tissue plasminogen activator (t-PA) and urokinase to enhance the body's natural clot-dissolving mechanisms. Additionally, nattokinase exhibits mild angiotensin-converting enzyme (ACE) inhibitory activity to help regulate blood pressure. The inclusion of calcium-L-methylfolate supports normal blood formation and the metabolism of homocysteine, a known cardiovascular risk factor. Nattokinn is marketed for the prevention and adjuvant therapy of cardiovascular diseases, including thrombosis, atherosclerosis, and hypertension.
- Brand names
- Nattokinn
- Other names
- NATTOKINN
02
Targets
ACE (Angiotensin Converting Enzyme)Fibrin (Factor Ia)PAI-1 (Plasminogen activator inhibitor type 1)
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