Drug intelligence / Profile preview

Natureheme-iron

Development stage
Unknown
Lead developer
Chung Shan Medical University
Modality
Small Molecules
Administration
Oral
01

Overview

Natureheme-iron is a heme-based iron dietary supplement evaluated by Chung Shan Medical University for its efficacy in improving iron absorption and antioxidant status in individuals with mild anemia. Unlike traditional inorganic iron supplements (such as ferrous sulfate), Natureheme-iron utilizes heme iron, which is absorbed via the heme carrier protein 1 (HCP1) in the intestinal mucosa. This pathway is more efficient and less prone to inhibition by dietary factors, potentially leading to better gastrointestinal tolerability. The supplement was studied in a randomized, double-blind, placebo-controlled trial (NCT02144311) at a dosage of 1000 mg (likely referring to the heme-iron complex) per day to assess its impact on hemoglobin levels, serum ferritin, and oxidative stress markers.

Brand names
Natureheme-iron
Other names
Natureheme ironsupplement-Chung Shan Medical University
02

Targets

SLC46A1 (Proton-coupled folate transporter)

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