nauclea officinalis extract

Nauclea officinalis extract is a botanical preparation derived from the stems, bark, or leaves of the plant Nauclea officinalis, a member of the Rubiaceae family traditionally used in Chinese medicine. The extracts contain a diverse array of phytochemicals including indole alkaloids (such as strictosamide, naucline, angustine), phenolic acids, pentacyclic triterpenoids, and flavonoids[1][2][3][4][5]. These compounds are associated with multiple pharmacological effects such as anti-inflammatory[9], antibacterial[2], antiviral[2], anti-tumor[2], neuroprotective (notably via cholinesterase inhibition)[7][8], and vasorelaxant activities[4]. Mechanistically, some isolated alkaloids inhibit acetylcholinesterase and butyrylcholinesterase enzymes (AChE/BChE), contributing to neuroprotection and potential cognitive benefits; others demonstrate direct anti-inflammatory or cytotoxic effects on cancer cells. The plant is primarily used for conditions like fever, pneumonia, pharyngolaryngitis (throat inflammation), enteritis (intestinal inflammation), and inflammatory diseases in traditional practice[5].

Other names

Nauclea officinalis water extractNauclea officinalis bark extractNauclea officinalis leaf extract