Drug intelligence / Profile preview

NausX

Development stage
Preclinical
Lead developer
Goldman Pharmaceutical Group
Modality
Small Molecules
Administration
Oral
01

Overview

NausX is a veterinary **oral chewable tablet** antiemetic developed by Goldman Pharmaceutical Group for use in dogs. Its active ingredient is **meclizine hydrochloride**, a **small-molecule H1 receptor blocker** with additional anticholinergic activity that helps prevent and relieve **nausea, vomiting, dizziness, and motion sickness associated with travel**; it is also used off-label for nausea related to vestibular disease in dogs. The product acts by reducing histaminergic and cholinergic signaling to the vestibular apparatus and the chemoreceptor trigger zone in the brain. Based on the provided context, it is marketed as an **over-the-counter animal drug** and its labeling has **not been approved by the FDA**.

Brand names
NausX
Other names
meclizine hydrochloridemeclizine HCl
02

Targets

HRH1 (Histamine H1 Receptor)

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