Drug intelligence / Profile preview

navacaprant

Development stage
Phase 3
Lead developer
Neumora Therapeutics
Modality
Small Molecules
Administration
Oral
01

Overview

Navacaprant is a small molecule, selective kappa opioid receptor antagonist being developed by Neumora Therapeutics for the treatment of major depressive disorder (MDD). It is designed to modulate dopamine and reward processing pathways. Navacaprant is administered orally at a dose of 80 mg once daily.

Other names
BTRX335140BTRX-335140BTRX 335140CYM53093CYM-53093CYM 53093XK5ILZ28KIXK-5ILZ28KIXK 5ILZ28KI
02

Targets

KOR (Kappa opioid receptor)

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