Drug intelligence / Profile preview

Navco-500

Development stage
Unknown
Lead developer
Vaqure Remedies
Modality
Small Molecules
Administration
Intravenous, Oral
01

Overview

Navco-500 is a generic formulation of the glycopeptide antibiotic **vancomycin**, developed and marketed by **Vaqure Remedies**. It is typically provided in a 500mg dosage form for parenteral administration. Vancomycin exerts its bactericidal effect by inhibiting the second stage of bacterial cell wall synthesis in susceptible gram-positive organisms. It specifically binds to the D-alanyl-D-alanine terminus of cell wall precursor units, thereby blocking the transglycosylation and transpeptidation steps required for peptidoglycan cross-linking. Navco-500 is primarily indicated for the treatment of serious or severe infections caused by susceptible strains of methicillin-resistant *Staphylococcus aureus* (MRSA) and other gram-positive bacteria, including endocarditis, septicemia, and bone infections. As a non-beta-lactam antibiotic, it serves as a critical therapeutic alternative for patients with beta-lactam allergies or infections resistant to other antibiotic classes.

Brand names
Navco-500Navco500Navco 500
Other names
vancomycin
02

Targets

D-Ala-D-Ala (D-Ala-D-Ala terminus)

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