Drug intelligence / Profile preview

Navstel

Development stage
Phase 3
Lead developer
Alcon
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

Navstel, also known as Next Generation Ophthalmic Irrigating Solution (NGOIS), is an intraocular irrigating solution developed by Alcon. It is a balanced salt solution (BSS) enriched with 0.015% hypromellose (HPMC), a viscoelastic polymer. Navstel is indicated for use during intraocular surgical procedures, such as cataract extraction and intraocular lens (IOL) implantation. The addition of hypromellose provides enhanced protection to the corneal endothelium by coating the tissue and reducing mechanical trauma and oxidative stress during surgery. It also helps maintain the structural integrity and volume of the anterior chamber. The product was approved by the FDA in 2008 (NDA 022193).

Brand names
Navstel
Other names
Next Generation Ophthalmic Irrigating Solution

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