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Nazoneem is an over-the-counter isotonic nasal spray marketed by Actor Pharma in South Africa. It is formulated with a combination of isotonic saline (sodium chloride) and *Azadirachta indica* (Neem) extract. The product is primarily indicated for nasal hygiene, the relief of nasal congestion, and the moisturizing of dry nasal passages. The saline component works through mechanical clearance, thinning mucus and washing away allergens, dust, and pollutants, while the Neem extract is included for its traditional anti-inflammatory and antimicrobial properties to soothe the nasal mucosa. It is used as a non-medicated alternative or adjunct for managing symptoms of allergic rhinitis, sinusitis, and common colds.
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