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NCI-9138 (also known as NSC 710305) is an investigational small molecule therapeutic that was evaluated by the National Cancer Institute (NCI) for the treatment of various malignancies. While specific structural details and its precise molecular target are not widely publicized in contemporary commercial pipelines, it was historically studied in early-phase clinical trials, including those for advanced solid tumors and hematologic malignancies such as chronic lymphocytic leukemia (CLL). The compound was part of the NCI's developmental therapeutics program aimed at identifying novel antineoplastic agents with unique mechanisms of action compared to standard cytotoxic chemotherapies.
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