Drug intelligence / Profile preview

nCPAP + poractant alfa

Development stage
Unknown
Lead developer
Chiesi
Administration
Inhalation, Intratracheal, Intranasal
01

Overview

A combination therapy approach for treating Respiratory Distress Syndrome (RDS) in premature infants. This therapy combines nasal Continuous Positive Airway Pressure (nCPAP) ventilation support with administration of poractant alfa (Curosurf), a natural porcine lung surfactant. The surfactant can be delivered via nebulization, thin catheter administration, or through brief intubation (InSurE method) while the infant is supported with nCPAP. This approach aims to provide non-invasive respiratory support while delivering surfactant therapy to compensate for the lack of endogenous surfactant in premature infants with RDS.

Other names
nCPAP with poractant alfanasal Continuous Positive Airway Pressure with poractant alfa
02

Targets

PS (Phosphatidylserine)

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