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NCR-300

Development stage
Phase 1
Lead developer
Nuwacell Biotechnologies
Modality
CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Lymphokine-Activated Killer Cells → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous, Intraperitoneal
01

Overview

NCR-300 is a cell therapy product composed of natural killer (NK) cells, under clinical development by Nuwacell Biotechnology. It is being investigated for the treatment of several cancers, including high grade ovarian serous carcinoma, endometrioid carcinoma, primary peritoneal carcinoma, acute myeloid leukemia (AML), fallopian tube carcinoma, and myelodysplastic syndrome. The drug is administered intravenously or intraperitoneally. Its mechanism of action involves immunologic cytotoxicity as a natural killer cell replacement therapy[1][2][4].

Other names
iNK cellsiPSC-derived natural killer cellshuman induced pluripotent stem cell derived natural killer cellsiNK Injection
02

Targets

NKG2DL (NKG2D ligand family)

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