Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
NCR400
- Development stage
- Preclinical
- Lead developer
- Anhui Zhongsheng Traceability Biotechnology
- Modality
- iPSCs → Pluripotent Stem Cells → Stem Cell Therapies → Cell Therapies
- Administration
- Transplantation
01
Overview
NCR400 is an investigational universal induced pluripotent stem cell (iPSC)-derived islet cell therapy being developed by Anhui Zhongsheng Traceability Biotechnology (also known as Nuwacell) for the treatment of diabetes mellitus. The therapy involves the differentiation of iPSCs into functional pancreatic islet cells, which are then transplanted into patients to replace damaged or dysfunctional endocrine cells. As a 'universal' therapy, NCR400 is engineered to be hypoimmunogenic, which may allow for transplantation without the requirement for long-term systemic immunosuppression. The program is currently in the IND-enabling stage and aims to restore endogenous insulin production and glycemic control in patients with insulin-dependent diabetes.
- Other names
- Universal isletiPSC-derived islet cells
Beyond the preview
Go deeper on NCR400.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on NCR400.