Drug intelligence / Profile preview

Nectero EAST System

Development stage
Unknown
Lead developer
Nectero Medical
Modality
Small Molecules
Administration
Intra-arterial, Percutaneous
01

Overview

**Nectero EAST System** is an investigational, single-use endovascular drug-device combination product developed by Nectero Therapeutics for small- to medium-sized infrarenal abdominal aortic aneurysm. The system uses a dual-balloon catheter to locally deliver a single dose of a stabilizer infusion solution containing pentagalloylglucose into the aneurysmal aortic wall. Pentagalloylglucose binds elastin and collagen, with the intended effect of reinforcing extracellular-matrix structural proteins, stabilizing the aortic wall, and slowing aneurysm enlargement and rupture risk. The product leaves no permanent implant and is being evaluated against surveillance in the randomized Phase 2/3 stAAAble study. ([alcami.com](https://www.alcami.com/news/alcami-supports-phase-ii-iii-trial-supply-of-the-nectero-east-system/))

Brand names
Nectero EAST SystemNectero EAST
Other names
Nectero Endovascular Aneurysm Stabilization Treatment System
02

Targets

ELN (Elastin)

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