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Negative Control Toothpaste

Development stage: Unknown
Lead developer: Church & Dwight
Modality: Small Molecules
Administration: Topical

Overview

Negative Control Toothpaste (Church & Dwight) is a fluoride-free dentifrice formulation used as a comparative control in clinical research conducted by Church & Dwight Company, Inc. It is specifically designed for use in intra-oral appliance (IOA) models to evaluate the efficacy of fluoride-containing toothpastes on enamel lesion remineralization. By excluding active remineralizing agents like sodium fluoride, this toothpaste provides a baseline for assessing the natural remineralization capacity of saliva and the relative performance of investigational dental products in preventing or treating dental caries.

Other names: Negative Control ToothpasteFluoride-free toothpasteNegative Control Toothpaste-Church & Dwight Company, Inc.-dental caries

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