Drug intelligence / Profile preview

NEK1

Development stage
Preclinical
Lead developer
Turbine
Modality
Small Molecules
01

Overview

NEK1 refers to a novel cancer therapy being co-developed by Turbine and Harmonic Discovery. This therapy is a kinase inhibitor designed to target the NIMA-related kinase 1 (NEK1), which has been identified as a 'dark kinase' and a cancer-driving target. Turbine utilizes its Simulated Cell™ platform for target identification and validation, including identifying synergistic co-targets and patient populations. Harmonic Discovery employs its generative chemistry platform for the design and development of these kinase inhibitors. The collaboration aims to create differentiated kinase inhibitor therapies for cancer.

02

Targets

NEK1 (NIMA related kinase 1)

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