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NEO-SV-01
- Development stage
- Preclinical
- Lead developer
- BioNTech
- Modality
- Peptide-based Cancer Vaccines → Cancer Vaccines → Therapeutic Vaccines → Vaccines & Immunotherapeutics
- Administration
- Subcutaneous
01
Overview
NEO-SV-01 is a neoantigen-based cancer vaccine developed for the treatment of a genetically defined subset of estrogen-receptor-positive cancers. It utilizes a personalized approach by identifying neoantigens present in an individual's tumor to create a customized vaccine intended to elicit a targeted immune response, specifically aiming to harness the body's T cells to recognize and attack cancer cells bearing these tumor-specific antigens[3]. The vaccine aims to amplify anti-tumor immunity and may be combined with other immunotherapeutic agents. NEO-SV-01 was developed using genomic and bioinformatic analyses to select the most immunogenic neoantigens for each patient, representing a targeted and individualized strategy within cancer immunotherapy.
- Brand names
- NEO-SV-01NEO-SV01NEO-SV 01
- Other names
- NEO-SV-01NEO-SV01NEO-SV 01
02
Targets
pMHC (Peptide-MHC complex family)
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