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NeoCura IM is an mRNA-based tumor microenvironment immunomodulator being developed by NeoCura for the treatment of solid tumors. The therapeutic candidate consists of mRNA sequences encoding immunomodulatory cytokines or other specific immunoregulatory factors. Upon delivery, NeoCura IM utilizes the patient's own cells to express these cytokines, thereby modifying the immunosuppressive tumor microenvironment, activating both innate and adaptive immune responses, and enhancing antitumor immunity. It is designed to be used either as a monotherapy or in combination with other immunotherapies, such as immune checkpoint inhibitors, tumor vaccines, or cell therapies, to achieve synergistic antitumor efficacy.
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