Drug intelligence / Profile preview

neomycin sulfate + fluocinolone acetonide

Development stage
Phase 4
Lead developer
Medimetriks Pharmaceuticals
Modality
Small Molecules
Administration
Topical
01

Overview

**Neomycin sulfate + fluocinolone acetonide** is a topical combination drug used primarily to treat skin infections that are either risk prone to or associated with inflammatory processes that are responsive to corticosteroids. It contains two active ingredients: **neomycin sulfate**, an aminoglycoside antibiotic that inhibits protein synthesis in a broad range of bacteria, and **fluocinolone acetonide**, a synthetic corticosteroid that reduces inflammation by activating the glucocorticoid receptor pathway, suppressing inflammatory gene expression and mediator release. Primary indications include dermatitis, eczema, psoriasis, and other corticosteroid-responsive dermatoses complicated by or at risk of bacterial infection[1][3][4][5][6][7][8].

Brand names
Neo-SynalarSynalar NNeotraCare
Other names
fluocinolone and neomycin topicalneomycin and fluocinolone
02

Targets

GR (Glucocorticoid receptor)Bacterial Ribosome

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