Drug intelligence / Profile preview

Neosalus (Exeltis)

Development stage
Unknown
Lead developer
Quinnova Pharmaceuticals
Modality
Small Molecules
Administration
Topical
01

Overview

Neosalus is a prescription topical skin barrier emollient developed by Exeltis USA for the management of various dermatoses, including dry skin, atopic dermatitis, and allergic contact dermatitis. It is formulated as a fragrance-free, non-comedogenic, water-soluble dressing containing active components such as free fatty acids, dimethicone, and glycerin. Neosalus works by forming a protective barrier on the skin surface to lock in moisture and shield the skin from external irritants. It is available in cream, foam, and lotion formulations and is classified as a prescription medical device. Clinical evaluations have also explored its potential antimicrobial properties against pathogens like *Escherichia coli* and methicillin-resistant *Staphylococcus aureus* (MRSA).

Brand names
NeosalusNeosalus Hydrating Topical Cream
02

Targets

SCLM (Stratum corneum lipid matrix)AQP3 (Aquaporin-3 channel protein)TGM1 (Transglutaminase 1)

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