Drug intelligence / Profile preview

Neoven

Development stage
Phase 4
Lead developer
Santa Farma
Modality
Small Molecules
Administration
Oral
01

Overview

Neoven is a phytotherapeutic pharmaceutical product containing 225 mg of *Ruscus aculeatus* (Butcher's Broom) extract per capsule. The extract is standardized for steroidal saponins, specifically **ruscogenin** and **neoruscogenin**, which are the primary active constituents responsible for its therapeutic effects. Neoven is primarily indicated for the treatment of **hemorrhoidal disease** (specifically stages II and III) and **chronic venous insufficiency**. It acts as a venotonic and vasoconstrictor agent, enhancing venous tone and reducing capillary permeability and filtration. Additionally, the drug exhibits anti-inflammatory and diuretic properties, which help to alleviate symptoms such as rectal bleeding, anal discomfort, itching, and edema. By improving the structural integrity of vascular cushions and reducing venous distension, Neoven serves as a non-surgical management option for symptomatic hemorrhoids.

Brand names
Neoven
Other names
Ruscus aculeatus extractButcher's broom extract
02

Targets

ADRA1A (α1A)ADRA2A (α2A)

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