Drug intelligence / Profile preview

nepafenac + tobramycin + dexamethasone + tropicamide

Development stage
Unknown
Lead developer
Novartis
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

This appears to be a combination ophthalmic medication containing four active ingredients: - **Nepafenac**: A nonsteroidal anti-inflammatory drug (NSAID) prodrug that reduces pain and inflammation, particularly after cataract surgery - **Tobramycin**: An aminoglycoside antibiotic that treats bacterial infections - **Dexamethasone**: A corticosteroid that reduces inflammation - **Tropicamide**: An anticholinergic agent that causes pupil dilation (mydriasis) and paralysis of accommodation (cycloplegia) This combination would likely be used in the context of ophthalmic surgery, particularly cataract surgery, to simultaneously address inflammation, prevent infection, and facilitate examination or surgical procedures.

02

Targets

GR (Glucocorticoid receptor)mAChR (Muscarinic acetylcholine receptors)Bacterial RibosomePGHS-1 (Prostaglandin G/H Synthase 1)

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