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nepafenac + tobramycin + dexamethasone + tropicamide
- Development stage
- Unknown
- Lead developer
- Novartis
- Modality
- Small Molecules
- Administration
- Ophthalmic
01
Overview
This appears to be a combination ophthalmic medication containing four active ingredients: - **Nepafenac**: A nonsteroidal anti-inflammatory drug (NSAID) prodrug that reduces pain and inflammation, particularly after cataract surgery - **Tobramycin**: An aminoglycoside antibiotic that treats bacterial infections - **Dexamethasone**: A corticosteroid that reduces inflammation - **Tropicamide**: An anticholinergic agent that causes pupil dilation (mydriasis) and paralysis of accommodation (cycloplegia) This combination would likely be used in the context of ophthalmic surgery, particularly cataract surgery, to simultaneously address inflammation, prevent infection, and facilitate examination or surgical procedures.
02
Targets
Bacterial RibosomeGR (Glucocorticoid receptor)mAChR (Muscarinic acetylcholine receptors)PGHS-1 (Prostaglandin G/H Synthase 1)
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