Drug intelligence / Profile preview

Nephrotect

Development stage
Unknown
Lead developer
Fresenius Kabi
Modality
Small Molecules, Peptides
Administration
Intravenous
01

Overview

Nephrotect is a specialized intravenous amino acid solution designed for parenteral nutrition in patients with acute or chronic renal failure. Developed by Fresenius Kabi, it is specifically formulated to meet the altered metabolic needs of patients with impaired kidney function, particularly those undergoing renal replacement therapies like hemodialysis or hemofiltration. The solution provides a balanced profile of essential and non-essential amino acids while minimizing nitrogen waste. A distinguishing feature is the inclusion of the dipeptide glycyl-L-tyrosine, which ensures the delivery of tyrosine—an amino acid often depleted in renal failure—in a highly soluble and bioavailable form. Clinical research, including studies at the University Hospital of the Canary Islands, has explored its use in optimizing nutritional status and potentially protecting renal function in contexts such as living donor kidney transplantation.

Brand names
Nephrotect
Other names
Amino acid solution for renal failure
02

Targets

Ribosome

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