NER1008

NER1008 is a rectal enema formulation containing polyethylene glycol 3350 (PEG3350), developed by Norgine for bowel cleansing prior to flexible sigmoidoscopy. It functions as an osmotic laxative, where the PEG3350 polymer retains water within the rectum and sigmoid colon. This increases the volume of the stool, leading to rectal distension and triggering the natural urge to evacuate, thereby clearing the distal colon of solid matter. This preparation is intended to provide a clear view for endoscopic procedures without the need for extensive dietary restrictions or oral bowel preparations. While it contains a pharmaceutical active ingredient, it is classified as a medical device in some clinical contexts.

Other names

PEG3350 enemaPEG-3350 enemaPEG 3350 enemapolyethylene glycol 3350 enema