nerolidol

Nerolidol is a naturally occurring **sesquiterpene alcohol** found in the essential oils of various plants, flowers, and herbs, commonly contributing a woody, floral, and citrus-like aroma[1][2][3][5][7]. Chemically, nerolidol exists in both *cis* and *trans* geometric isomers and as two enantiomers. Widely used in perfumes, cosmetics, food flavorings (FDA-approved), and as an industrial fragrance, nerolidol also acts as an intermediate in the synthesis of vitamin E and K1[2][5]. In preclinical and experimental studies, it demonstrates **antifungal, antibacterial, antioxidant, anti-inflammatory, anti-parasitic, anti-nociceptive, anticancer**, and penetration-enhancing properties, though medical use is not established[1][2][4][6]. Its high hydrophobicity facilitates penetration through biological membranes, making it valuable in skin and transdermal formulations[2][4].

Other names

peruviol3,7,11-trimethyl-1,6,10-dodecatrien-3-ol3,7,11-trimethyl-1,6,10-dodecatriene-3-ol3,7,11-trimethyldodeca-1,6,10-trien-3-ol3-hydroxy-3,7,11-trimethyl-1,6,10-dodecatrienenerolidostirrupHuMbertiol1,6,10-dodecatrien-3-ol,3,7,11-trimethyl-cas 7212-44-4cas7212-44-4cas-7212-44-4