Drug intelligence / Profile preview

netakimab

Development stage
Phase 3
Lead developer
Biocad
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Administration
Subcutaneous
01

Overview

Netakimab is a humanized recombinant IgG1 monoclonal antibody that targets and neutralizes interleukin-17A (IL-17A), a pro-inflammatory cytokine involved in the pathogenesis of several autoimmune diseases. By inhibiting IL-17A, netakimab reduces inflammation and immune-mediated tissue damage. It is administered via subcutaneous injection and has demonstrated efficacy in moderate-to-severe plaque psoriasis, ankylosing spondylitis, and psoriatic arthritis. Netakimab was developed by Biocad and has been approved for use in Russia and Belarus for these indications[3][4][5][6][7][8].

Brand names
Efleira
Other names
NTKImmunoglobulin g1, anti-(human interleukin 17) (human-lama glama monoclonal heavy chain), disulfide with human monoclonal light chain, dimer
02

Targets

IL-17A (Interleukin-17A)IL17F (Interleukin 17F)

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