Drug intelligence / Profile preview

Neucrylate

Development stage
Discontinued
Lead developer
Valor Medical
Modality
Small Molecules
Administration
Intravascular
01

Overview

Neucrylate is a liquid embolic medical device developed by Valor Medical for the treatment of cerebral aneurysms and arteriovenous malformations (AVMs). The active component is 1-hexyl n-cyanoacrylate, a compound that functions as a moldable liquid embolic agent. During clinical application, it is typically injected into the vascular abnormality during temporary balloon occlusion of the parent vessel. The device contains a metal component to provide radiopacity for visualization under fluoroscopy. Neucrylate's regulatory path was terminated following a legal investigation where Valor Medical and its executives pleaded guilty to concealing adverse toxicity reports from the FDA during the premarket review process.

Brand names
Neucrylate
Other names
1-hexyl n-cyanoacrylate

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