Drug intelligence / Profile preview

Neupron

Development stage
Preclinical
Lead developer
AxoNeural Therapeutics
Modality
Nanoparticles → Drug Delivery Systems, Therapeutic Enzymes → Recombinant Proteins and Enzymes
Administration
Intravenous
01

Overview

**Neupron** is a preclinical intravenous nanoparticle-based enzyme therapy developed by AxoNeural Therapeutics for acute traumatic spinal cord injury. It encapsulates the antioxidant enzymes catalase and superoxide dismutase to neutralize injury-associated reactive oxygen species, reduce oxidative stress, and limit the secondary degeneration cascade after spinal cord trauma. In preclinical rat contusion studies, intravenous administration after injury was reported to reduce secondary injury progression and improve locomotor recovery. ([sbir.gov](https://www.sbir.gov/portfolio/1712485))

Other names
Neupron

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