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Drug intelligence / Profile preview
Neurexan
- Development stage
- Phase 2
- Lead developer
- Heel
- Modality
- Small Molecules
- Administration
- Oral, Sublingual
01
Overview
Neurexan is a multi-component homeopathic medicinal product developed by Biologische Heilmittel Heel GmbH, primarily indicated for the treatment of nervous restlessness, stress-related symptoms, and sleep disturbances such as short-term insomnia. The formulation consists of four active ingredients: *Passiflora incarnata* (passionflower), *Avena sativa* (oats), *Coffea arabica* (coffee), and *Zincum isovalerianicum* (zinc valerate). Neurexan is designed to modulate the stress response by stabilizing the hypothalamic-pituitary-adrenal (HPA) axis and reducing stress-induced cortisol levels. Unlike conventional hypnotics, it aims to improve sleep efficiency and daytime performance without causing sedation, dependency, or morning grogginess. Clinical research, including Phase 2 trials, has utilized polysomnography (PSG) and electroencephalography (EEG) to evaluate its efficacy in addressing insomnia and stress-induced physiological changes.
- Brand names
- Neurexan
02
Targets
DRD (Dopamine receptors)BZD site (GABA-A receptor benzodiazepine site)ADRA2A (α2A)
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