Neuriterx

**Neuriterx** is a topical over-the-counter cream containing **0.05% or 0.075% capsaicin**, a naturally occurring compound derived from chili peppers, formulated for the symptomatic relief of neuropathic pain symptoms such as burning, tingling, numbness, swelling, and poor balance associated with peripheral neuropathy. It acts primarily by activating **transient receptor potential cation channel subfamily V member 1 (TRPV1)** on nociceptive nerve fibers, leading to initial depolarization followed by defunctionalization—a prolonged desensitization that reduces pain signaling through mechanisms including substance P depletion, mitochondrial disruption, and nerve terminal retraction. Developed as a patent-pending neuropathy management product by **Semprae Laboratories Inc.**, it provides rapid relief within minutes of application without systemic absorption risks typical of prescription analgesics.[3][4][6][9]

Brand names

Neuriterx

Other names

Neuriterx 0.05%Neuriterx 0.075%