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NeuroRestore
- Development stage
- Unknown
- Lead developer
- AlzeCure Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
NeuroRestore is a drug development platform and series of small molecule candidates developed by AlzeCure Pharma, with ACD856 as the lead compound. It functions as a positive allosteric modulator (PAM) of Tropomyosin receptor kinase (Trk) receptors, specifically enhancing the signaling of neurotrophins such as Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF). By strengthening these pathways, the drug aims to improve cognitive function, learning, and memory, while potentially offering neuroprotective and disease-modifying effects. It is primarily being developed for Alzheimer's disease but has potential applications in Parkinson's disease, traumatic brain injury, sleep apnea, depression, and obesity.
02
Targets
NTRK1 (Tropomyosin-related receptor kinase A)NTRK2 (Tropomyosin-related kinase receptor type B)Trk (Trk receptor family)
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