NeuroStilbene

NeuroStilbene is a proprietary **intranasal nano-formulation of pterostilbene** developed by Therapeutic Solutions International for delivery to the brain. It is described as a diluted preparation of NanoStilbene, a more concentrated nanoemulsion of nanoparticle pterostilbene, and is intended to enhance central nervous system exposure by bypassing or traversing the blood-brain barrier after intranasal administration. Preclinical descriptions attribute its activity to suppression of neuroinflammation, including inhibition of microglial production of inflammatory cytokines such as interleukin 1 beta, interleukin 6, and tumor necrosis factor alpha, together with neuroprotective and neuroregenerative effects including induction of brain-derived neurotrophic factor, nerve growth factor, fibroblast growth factor 1, and fibroblast growth factor 2, protection from apoptosis, and stimulation of endogenous neural stem cell proliferation. The product has been discussed for potential use in brain tumors and neurodegenerative diseases, but based on the provided context it appears to be marketed as a supplement or nutraceutical formulation rather than an FDA-approved pharmaceutical drug.

Brand names

NeuroStilbene

Other names

intranasal nanoparticle pterostilbenenano-formulated pterostilbene