Drug intelligence / Profile preview

Neuroton (Ain Shams University)

Development stage
Unknown
Lead developer
Ain Shams University
Modality
Small Molecules
Administration
Oral, Intramuscular
01

Overview

Neuroton is a Vitamin B complex formulation, primarily manufactured by Amoun Pharmaceutical Co., which typically contains thiamine (B1), pyridoxine (B6), and cyanocobalamin (B12). In the context of clinical research led by Ain Shams University, a version including folic acid (B9) is being evaluated for its analgesic efficacy in postoperative pain management, specifically for obstetric patients undergoing Cesarean sections. The drug is utilized as an adjuvant in multimodal analgesia to enhance the effects of standard treatments like paracetamol and NSAIDs while potentially reducing opioid requirements. Its mechanism of action involves the neurotropic properties of B vitamins, which support nerve regeneration and modulate pain signaling pathways by enhancing inhibitory neurotransmission (e.g., GABAergic and serotonergic systems) and stabilizing neuronal membranes.

Brand names
Neuroton
Other names
Vitamin B complexVitamin B1 + B6 + B9 + B12
02

Targets

GABA-B (Gamma-aminobutyric acid receptor type B)5-HT (Serotonin receptors)NaV (Voltage-gated sodium channels)

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