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Drug intelligence / Profile preview
neurotrophic factor-expressing mesenchymal stem cell
- Development stage
- Unknown
- Lead developer
- BrainStorm Cell Therapeutics
- Modality
- Mesenchymal Stem Cells → Adult Stem Cells → Stem Cell Therapies → Cell Therapies, Gene Therapies
01
Overview
**Neurotrophic factor-expressing mesenchymal stem cell** is an Acıbadem Labcell cellular-therapy product descriptor for mesenchymal stem cells engineered to express neurotrophic factors, including neurotrophin-3, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor. The intended biology is local secretion of trophic factors to support neuronal survival, neuroprotection, regeneration, and repair. Acıbadem Labcell lists this as a cell-therapy product category, but the public source does not identify a unique development code, a defined cell source, a clinical indication, administration route, or clinical-development phase.
- Other names
- Neurotrophic factor-expressing mesenchymal stem cellNTF3/BDNF/GDNF MSCNörotrofik Faktör Eksprese Eden Mezenkimal Kök Hücre
02
Targets
NCAM1 (Neural cell adhesion molecule 1)GFRA1 (Glial cell line-derived neurotrophic factor family receptor alpha 1)SDC3 (Syndecan-3 / SDC3)NTRK1 (Tropomyosin-related receptor kinase A)NTRK2 (Tropomyosin-related kinase receptor type B)NTRK3 (Tropomyosin receptor kinase C)NGFR (p75NTR)
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