Drug intelligence / Profile preview

neutral xylooligosaccharides

Development stage
Discontinued
Modality
Microbiome-Derived Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Neutral xylooligosaccharides are a mixture of short-chain xylose oligomers derived from xylan, typically produced from plant biomass such as hardwood pulp. In the provided public-source evidence, they are described as orally administered oligosaccharides evaluated for prevention of atopic dermatitis-like disease in mice, where they did **not** show a significant preventive effect, in contrast to acidic xylooligosaccharides. Their putative therapeutic concept is as a non-absorbed oligosaccharide that could modulate the gut environment and downstream immune responses rather than acting on a single defined molecular target; however, there is no clear evidence here of clinical development as a standardized pharmaceutical product.

Other names
neutral xylooligosaccharidesxylooligosaccharidesXOS
02

Targets

GSR (Glutathione reductase)TLR4 (Toll-like receptor 4)

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