Drug intelligence / Profile preview

new cryoprecipitate

Development stage
Discontinued
Lead developer
The University of Tokyo Hospital
Modality
Recombinant Proteins and Enzymes
Administration
Intravenous
01

Overview

"New cryoprecipitate" is an investigational, blood-derived coagulation factor concentrate prepared using an optimized method to treat obstetric critical hemorrhage. It contains high concentrations of fibrinogen, Factor VIII, Factor XIII, and von Willebrand factor. Developed and tested at The University of Tokyo Hospital, this product is intended to provide a more potent and rapid source of fibrinogen compared to conventional cryoprecipitate preparation methods. In clinical evaluation (jRCTs032210302), it demonstrated the ability to significantly increase plasma fibrinogen levels and support hemostasis in women with severe postpartum hemorrhage, although the primary trial was terminated early due to insufficient enrollment.

Other names
investigational cryoprecipitate
02

Targets

Coagulation Factor XIIIBB-031 (Von Willebrand factor)F8 (Coagulation Factor VIIIa)

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