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New World alphavirus multivalent vaccine

Development stage: Preclinical
Lead developer: Hawaii Biotech
Modality: Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics

Overview

New World alphavirus multivalent vaccine is a **multivalent recombinant subunit protein vaccine** being developed by Hawaii Biotech for prophylaxis against major New World equine encephalitis alphaviruses. The candidate is described as combining antigens from **Venezuelan equine encephalitis virus**, **Eastern equine encephalitis virus**, and **Western equine encephalitis virus** to induce protective immunity against the corresponding encephalitic diseases. Based on the provided pipeline context, it is a **preclinical vaccine program** and appears intended as a broad-spectrum alphavirus immunization approach rather than a therapeutic product.

Other names: New World Alphavirus vaccine

Targets

VEEV E polyprotein (Venezuelan equine encephalitis virus envelope polyprotein)WEEV structural protein (Western equine encephalitis virus structural polyprotein)EEEV antigen (Eastern equine encephalitis virus antigen)

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