Drug intelligence / Profile preview

Newcastle disease virus vaccine

Development stage
Discontinued
Lead developer
CastleVax
Modality
Vaccines & Immunotherapeutics
Administration
Oral, Intranasal, Ophthalmic, Inhalation, Subcutaneous, In Ovo
01

Overview

Newcastle disease virus (NDV) vaccine is used for immunization against Newcastle disease in poultry. The vaccine is available in different forms including live virus vaccines and recombinant vector vaccines. The vector vaccines use herpesvirus of turkeys (HVT) as a vector by inserting the fusion (F) gene from Newcastle disease virus into the HVT genome. NDV vaccines work by stimulating a systematic immune response, especially mucosal immunity in the respiratory tract. The vaccine helps reduce mortality and severity of NDV symptoms in poultry and decreases the amount of virus spread.

Brand names
VECTORMUNE HVT NDV & RISPENSVECTORMUNE HVT NDV & SB1Newcastle LaSota
Other names
Newcastle Disease Vaccine, B1 Type, LaSota Strain
02

Targets

HN (Hemagglutinin-neuraminidase protein)HMPV F (Human metapneumovirus fusion protein)

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